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Giloy: The Anti-Viral Herb

Giloy: The Anti-Viral Herb

आयुर्वेद में गिलोय के विशिष्ट औषधीय गुणों के कारण ‘अमृत’ की संज्ञा दी गई है. गिलोय [Tinospora cordifolia] विषाणु जनित रोगों में मुख्य रूप से उपयोगी है चूँकि पौधों का चिकित्सीय उपयोग 4000-5000 ईसा पूर्व पुराना है जिसमे भारत और चीन दवाओं के रूप में पौधों का उपयोग पहले से करते आ रहे है. इसी कड़ी में आज हम Giloy; The Anti viral herb की औषधीय गुणों पर प्रकाश डालेंगे. 

Giloy Botanical Classification

heart-leaved moonseed, guduchi, giloy leaf

गिलोय [Giloy] का Botanical Name Tinospora cordifolia, Family: Menispermaceae है. यह आसानी से मिलने वाला Shrub है जिसका उल्लेख प्राचीन औषध विज्ञान ‘आयुर्वेद’ में भी मिलता है. 

Propagation technique

गिलोय [Giloy; The Anti viral herb] के तने का उपयोग ज्यादातर खेती के लिए करते है. यह सभी प्रकार की मिट्टी में आसानी से उग जाती है विशेषकर जल निकास की सुविधा होनी चाहिए. जून-जुलाई में इसके cutting लगाई जाती है. घर पर गमलों में भी आसानी से इसे उगा सकते है.

Phytochemical's of Giloy

Giloy [T. cordifolia] में मुख्य रूप से Alkaloids, Glycosides, Steroids, Sesquiterpenoids, Essential oils, Fatty acids और Polysaccchrides. Alkaloids में Berberine, Bitter gilonin, Non-glycoside gilonin gilosterol प्रमुख है. Bitter gilonin content गिलोय में कड़वापन के लिए Responsible होता है. 

Medicinal properties of Giloy

प्राचीन आयुर्वेद पद्धति में उल्लेख मिलता है कि Giloy  [T. cordifolia] का use General tonic, Anti-allergic, Anti-diabetic, Anti-inflammatory, Anti-Arthritic, Antipyretic and Anti-periodic जैसे Health Problems में medicine के तौर पर होती है.

Research Database of Giloy

वैश्विक स्तर गिलोय पर हुए Research के अनुसार 1000 से भी ज्यादा research  material Science Direct Database पर अबतक published हो चुके है जिसमे 125 से ज्यादा Book Chapters और 10 से ज्यादा Encyclopedia pages भी शामिल है. इस database में 500 से ज्यादा Research Article तथा 150 से भी ज्यादा Review Article अब तक शामिल हो चुके है.

Pharmacological activities of Giloy

अब तक हुए Research के अनुसार गिलोय का use modern medicine के तौर पर निम्न रोगों के treatment में किया जा रहा है…

Immunomodulatory activity

इस पौधे का उपयोग खास तौर पर रोग प्रतिरोध क्षमता को बढाने और शरीर को infection resistance बनाने के लिए किया जाता है. BMC Complementary & Alternate Medicine (2011) में published research से पता चलता है कि गिलोय के whole plant का Aqueous extract का use body immunity बढाने में कारगर पाया गया. Plant में पाए जाने वाले Glycosides जैसे Cordifolioside A, Tinocordiside and Syrigin Immunomodulatory activity के लिए responsible होते है.

Antioxidant activity

Journal of Pharmaceutical & Bioallied Sciences (PubMed) में published report के अनुसार गिलोय पाए गए Alkaloid, Diterpenoid lactone जैसे (-)Epicatechin, Tinosporin, Isocolumbin और Palmatine आदि antioxidant activity के लिए responsible होते है.

Hepatoprotective activity

Romanian Society of Surgery Magazine’s (Chirurgia) report के अनुसार गिलोय में पाए जाने वाले Alkaloids और Terpenoids जिसमें मुख्य रूप से Magnoflorin, Tinosporin, Isocolumbin, Palmatine, Tetrahydropalmatine होते है जिनका उपयोग jaundice जैसे liver से related disease के treatment में आसानी से किया जा सकता है.

Anti-inflammatory

गिलोय [Giloy; The Anti viral herb] में पाए जाने वाले Diterpenoid lactones जैसे Furanolactone, Tinosporin, Tinosporide, Jateorine, Columbin, Clerodane derivatives का use Anti-inflammatory medicine के रूप में किया जा रहा है. Rats में हुए एक ताज़ा Research के अनुसार T. cordifolia stem के Aqueous extract को ज्यादा असर कारक पाया गया.

Anti-diabetic activity

In-Vitro and In-Vivo studies के आधार पर माना गया है कि Giloy [T. cordifolia] stem में पाए जाने वाले Berberine, choline, Tembetarine, Palamtine, Jatrorrhizine Alkaloid के माध्यम से Diabetes का treatment किया जा सकता है. गिलोय के नियमित सेवन से diabetes होने का risk काफी कम हो जाता है.

Anti-malarial activity

गिलोय में पाए जाने वाले मुख्य घटक Tinosporin और Furanoid diterpene की पहचान मलेरिया रोधी तत्व के रूप में किया गया है. इस तत्व का उपयोग Hyper reactive मलेरिया के उपचार के लिए किया जाता है.

Anti Juandic

गिलोय के पत्तों का पेस्ट का सेवन छाछ के साथ करने पर पीलिया के इलाज के लिए लाभदायक होता है. परन्तु यह किसी योग्य आयुर्वेदिक चिकित्सक के देख-रेख में ही करना चाहिए.

Anti-venom property

गिलोय में anti venom तत्व पाए जाते है जिनका उपयोग सांप और बिच्छु के जहर को ख़त्म करने के लिए कुछ अन्य औषधी के साथ मिला कर किया जाता है. 

Other activities

उपरोक्त औषधीय उपयोग के अलावा अन्य activity के लिए भी गिलोय का use किया जाता है जैसे- Hypoglycemic activity, Cardioprotective effect,  Antifeedant activity, Gastroprotective activity, Analgesic activity, Antidiarrhoel activity, Antiulcer activity, Neuroprotective effect, Antidepressant activity, Antifertility effect,  Antitumor activity, Antibacterial activity, Anticancer activity and Antipyretic activity इत्यादि.

Side effects of Giloy

सबसे महत्वपूर्ण गिलोय रक्त शर्करा (Blood Sugar) के स्तर को कम करता है इसलिए मधुमेह रोगियों इसका सेवन सावधानी के साथ आयुर्वेदिक चिकित्सक की निर्देशानुसार करना चाहिए इसके अलावा गर्भावस्था और स्तनपान के दौरान गिलोय के सेवन किसी भी रूप में नही करने की सलाह दी जाती है.

Marketed product

भारतीय बाजारों में गिलोय घन वटी, गिलोय स्टेम जूस तथा गिलोय पाउडर के रूप में उपलब्ध है. 

Conclusion

गिलोय से लगभग हर तरह के रोगों का उपचार किया जा सकता है और इसके औषधीय गुणों को लेकर निरंतर अनुसन्धान हो रहे है. गिलोय के इन्हीं गुणों के कारण आयुर्वेद में ‘अमृत’ उपनाम से जाना जाता है.

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